Category Archives: Uncategorized

AudioHelicase Special: How foundational research takes medicines from lab to shelf

March 25, 2024Uncategorizedaudiohelicase

In this episode of AudioHelicase, we sit down with three Whitehead Institute researchers driving breakthroughs in disease treatment. Join us as we explore some of the toughest challenges they’re overcoming to move transformative therapies from lab bench to your medicine cabinet.

Credits:
Interviews, production, and hosting by Shafaq Zia.

Music and sound effects:
Crescent Bloom by Kai Engel (CC BY-NC 4.0)
OBJPlls-INT_Pills Rattling by Alessia Pultrone (CC BY-NC 4.0)
Asthma Inhaler — Sprayed/ Dispensed 2 times by MutilatorBCB (CC0 1.0)
Velcro 7 by CassieTee (CC BY-NC 3.0)

Illustration: DrawImpacts

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AudioHelicase Special: Getting a handle on hibernation

April 3, 2023Uncategorizedaudiohelicase

Whitehead Institute Member Siniša Hrvatin discusses his research on the neuroscience of hibernation.

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AudioHelicase Special: RNA in health and disease

May 19, 2021Uncategorizedaudiohelicase

Whitehead Institute researchers Silvi Rouskin, Ankur Jain, and David Bartel discuss how their RNA research connects to health and disease, including viral infections and neurodegeneration. This podcast is part of a multimedia series on RNA.

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AudioHelicase Special: Rebuilding a Body

February 8, 2021Uncategorizedbiology, biology podcast, development, evolution, regeneration, regenerative medicine, science communication, science podcastaudiohelicase

In this special episode of AudioHelicase, we talk to three researchers about the cells in our bodies that can regenerate – and those that can’t. We ask, why can some cells no longer renew themselves? And, importantly, can we change that? This podcast is part of our multimedia series, Cells Over Time.

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Whitehead Institute’s Silvi Rouskin on solving the structure of the coronavirus genome

October 13, 2020Uncategorizedbiochemistry, biology, biology podcast, coronavirus, covid, covid-19, genome, podcast, RNA, rna structure, sars-cov-2, science communication, science podcast, structural biology, Whitehead Instituteaudiohelicase

In this episode of AudioHelicase Podcast, Whitehead Fellow Silvi Rouskin discusses her research on solving the structure of the novel coronavirus’s RNA genome, with the goal of revealing weak points in the virus’s gene regulation that new drugs could potentially target.

Music: “Versailles” by Pierce Murphy (CC-BY 4.0). Produced by Conor Gearin.

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Whitehead Institute’s Olivia Corradin on a New Way to Probe Disease Genetics

August 3, 2020Uncategorizedbiology, genetics, genomics, multiple sclerosis, neuroscience, science, science communication, science podcast, Whitehead Instituteaudiohelicase

On this episode of AudioHelicase podcast, Whitehead Fellow Olivia Corradin talked about investigating the genetic underpinnings of diseases through a new technique she developed, the outside variant approach. Applying the method to study the autoimmune disease multiple sclerosis (MS), Corradin and colleagues identified a role for a cell type in the brain in MS, offering a new way of understanding the disease. She also discussed running a lab during the COVID-19 pandemic, and evaluating scientific information in a time of uncertainty.

Music: “Versailles” by Pierce Murphy (CC-BY 4.0). Produced by Conor Gearin.

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Whitehead’s Jing-Ke Weng on COVID-19 treatments taking root in plant science

June 8, 2020Uncategorizedbiology, covid, covid research, covid-19, medicinal plants, natural products, plant science, science, science communication, science podcast, Whitehead Instituteaudiohelicase

Plants have been used as medicine for thousands of years; could they contribute to a solution to the COVID-19 pandemic? This is what Whitehead Institute Member Jing-Ke-Weng set out to address in a new paper, published May 20 in the journal Molecular Plant.

We talked to Weng about an herbal treatment being used to treat COVID-19 in China derived from Traditional Chinese Medicine, the work necessary for such a treatment to be translated to an FDA-approved drug, and why the COVID-19 pandemic underscores the need for basic, fundamental research in plant science and beyond.

Music: “Versailles” by Pierce Murphy (CC-BY 4.0), “The Minutes” by Scott Gratton (CC-BY-NC 4.0) Produced by Eva Frederick and Conor Gearin.

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AudioHelicase Special: The Conductors of the Cell’s Symphony

March 18, 2020Uncategorizedaudiohelicase

In this special episode of AudioHelicase podcast, we’re taking a look at how our researchers are identifying the key players that help conduct the cell’s symphony — the proteins and molecules that direct many other parts of the cell on when and how to do their jobs. The episode features highlights from interviews with Whitehead Institute Members David Sabatini, Mary Gehring, and Iain Cheeseman.

Music: “Versailles” by Pierce Murphy (CC-BY 4.0), “The Little Robot” by Forget the Whale (CC-BY-NC 4.0)

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Whitehead’s Mary Gehring discusses how gene regulation can be passed from one generation to the next

April 11, 2018Uncategorizedaudiohelicase

In this episode of AudioHelicase, Whitehead Institute Member Mary Gehring discusses how her research on the plant Arabidopsis thaliana reveals how gene regulation can be passed from one generation to the next.

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